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Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides.
Thompson, Andrew M; Marshall, Andrew J; Maes, Louis; Yarlett, Nigel; Bacchi, Cyrus J; Gaukel, Eric; Wring, Stephen A; Launay, Delphine; Braillard, Stephanie; Chatelain, Eric; Mowbray, Charles E; Denny, William A.
Afiliação
  • Thompson AM; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. Electronic address: am.thompson@auckland.ac.nz.
  • Marshall AJ; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Maes L; Laboratory for Microbiology, Parasitology and Hygiene, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium.
  • Yarlett N; Haskins Laboratories, Pace University, NY 10038, USA.
  • Bacchi CJ; Haskins Laboratories, Pace University, NY 10038, USA.
  • Gaukel E; Scynexis, Inc., Research Triangle Park, NC 27713, USA.
  • Wring SA; Scynexis, Inc., Research Triangle Park, NC 27713, USA.
  • Launay D; Drugs for Neglected Diseases initiative, 15 Chemin Louis Dunant, 1202 Geneva, Switzerland.
  • Braillard S; Drugs for Neglected Diseases initiative, 15 Chemin Louis Dunant, 1202 Geneva, Switzerland.
  • Chatelain E; Drugs for Neglected Diseases initiative, 15 Chemin Louis Dunant, 1202 Geneva, Switzerland.
  • Mowbray CE; Drugs for Neglected Diseases initiative, 15 Chemin Louis Dunant, 1202 Geneva, Switzerland.
  • Denny WA; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
Bioorg Med Chem Lett ; 28(2): 207-213, 2018 01 15.
Article em En | MEDLINE | ID: mdl-29191556

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tripanossomíase Africana / Bibliotecas de Moléculas Pequenas / Nitroimidazóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tripanossomíase Africana / Bibliotecas de Moléculas Pequenas / Nitroimidazóis Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article