Pseudohyponatraemia, hypercholesterolaemia, and primary biliary cirrhosis.
J Clin Pathol
; 42(2): 167-71, 1989 Feb.
Article
em En
| MEDLINE
| ID: mdl-2921358
ABSTRACT
A 62 year old woman with primary biliary cirrhosis was found to have a plasma sodium concentration of 115 mmol/l. Follow up showed this to be a "pseudohyponatraemia" due to a massively raised serum cholesterol concentration of 78 mmol/l. Electrophoresis of serum lipoproteins and of the lipoproteins and apolipoproteins in fractions isolated on density-gradient ultracentrifugation showed that the major portion of the serum cholesterol was being transported with lipoprotein-X. Low density lipoprotein-cholesterol concentration was also raised. Lipoprotein-X contained, in addition to albumin and apolipoprotein C, apolipoprotein E. This case is of interest because of the degree of hypercholesterolaemia, its association with pseudohyponatraemia, and the unequivocal demonstration of apolipoprotein E associated with lipoprotein-X.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipercolesterolemia
/
Hiponatremia
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Cirrose Hepática Biliar
Limite:
Female
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Humans
/
Middle aged
Idioma:
En
Revista:
J Clin Pathol
Ano de publicação:
1989
Tipo de documento:
Article