Two Distinct Clinical Courses of Human Cowpox, Germany, 2015.
Viruses
; 9(12)2017 12 07.
Article
em En
| MEDLINE
| ID: mdl-29215552
ABSTRACT
Here we present two cases of human infection with cowpox virus with distinct clinical courses. A series of clinical photographs documents lesion progression over time. In the first case-an unvaccinated young veterinary assistant-a pustule was treated locally with cortisone. The lesion turned into a large ulcer accompanied by severe lymphadenitis. Based on her close contact to a sick stray cat, infection with cowpox virus was assumed and confirmed by virus isolation, PCR, and serology. The clinical course took up to eleven months until healing of the wound was complete. Transmission of cowpox virus from the cat was likely because a skin swab was PCR-positive and the cat had a high titer of anti-orthopoxvirus antibodies. In contrast, a rather mild clinical course of cowpox was confirmed in a 49-year-old male farmer vaccinated against smallpox. Only a small eschar developed, and wound closure was complete after 6 weeks.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pele
/
Zoonoses
/
Varíola Bovina
/
Vírus da Varíola Bovina
Limite:
Animals
/
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Viruses
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Alemanha