Your browser doesn't support javascript.
loading
Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity.
Wei, BinQing; Gunzner-Toste, Janet; Yao, Hui; Wang, Tao; Wang, Jing; Xu, Zijin; Chen, Jinhua; Wai, John; Nonomiya, Jim; Tsai, Siao Ping; Chuh, Josefa; Kozak, Katherine R; Liu, Yichin; Yu, Shang-Fan; Lau, Jeff; Li, Guangmin; Phillips, Gail D; Leipold, Doug; Kamath, Amrita; Su, Dian; Xu, Keyang; Eigenbrot, Charles; Steinbacher, Stefan; Ohri, Rachana; Raab, Helga; Staben, Leanna R; Zhao, Guiling; Flygare, John A; Pillow, Thomas H; Verma, Vishal; Masterson, Luke A; Howard, Philip W; Safina, Brian.
Afiliação
  • Wei B; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Gunzner-Toste J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Yao H; WuXi AppTec , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Wang T; WuXi AppTec , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Wang J; WuXi AppTec , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Xu Z; WuXi AppTec , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Chen J; WuXi AppTec , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Wai J; WuXi AppTec , 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Nonomiya J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Tsai SP; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Chuh J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Kozak KR; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Liu Y; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Yu SF; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Lau J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Li G; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Phillips GD; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Leipold D; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Kamath A; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Su D; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Xu K; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Eigenbrot C; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Steinbacher S; Proteros Biostructures GmbH , Bunsenstrasse 7a, D-82152 Martinsried, Germany.
  • Ohri R; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Raab H; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Staben LR; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Zhao G; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Flygare JA; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Pillow TH; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Verma V; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Masterson LA; Spirogen, QMB Innovation Centre, 42 New Road, London E1 2AX, United Kingdom.
  • Howard PW; Spirogen, QMB Innovation Centre, 42 New Road, London E1 2AX, United Kingdom.
  • Safina B; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
J Med Chem ; 61(3): 989-1000, 2018 02 08.
Article em En | MEDLINE | ID: mdl-29227683
Assuntos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Catepsina B / Imunoconjugados / Descoberta de Drogas / Peptidomiméticos Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Catepsina B / Imunoconjugados / Descoberta de Drogas / Peptidomiméticos Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos