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Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy.
Zheng, Hanqiu; Bae, Yangjin; Kasimir-Bauer, Sabine; Tang, Rebecca; Chen, Jin; Ren, Guangwen; Yuan, Min; Esposito, Mark; Li, Wenyang; Wei, Yong; Shen, Minhong; Zhang, Lanjing; Tupitsyn, Nikolai; Pantel, Klaus; King, Chadwick; Sun, Jan; Moriguchi, Jodi; Jun, Helen Toni; Coxon, Angela; Lee, Brendan; Kang, Yibin.
Afiliação
  • Zheng H; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA.
  • Bae Y; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Room R814 BCM225, Houston, TX 77030, USA.
  • Kasimir-Bauer S; Department of Gynecology and Obstetrics, University Hospital Essen, Essen, Germany.
  • Tang R; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA.
  • Chen J; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA.
  • Ren G; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA.
  • Yuan M; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA.
  • Esposito M; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA.
  • Li W; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA.
  • Wei Y; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA.
  • Shen M; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA.
  • Zhang L; Department of Pathology, University Medical Center of Princeton, Plainsboro, NJ, USA; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
  • Tupitsyn N; Laboratory of Hematopoiesis Immunology, Cancer Research Center, Moscow, Russia.
  • Pantel K; Department of Tumor Biology, University Medical Center Hamburg-Eppendorf, Center of Experimental Medicine, Hamburg, Germany.
  • King C; Oncology Research, Amgen Inc., Thousand Oaks, CA 91320, USA.
  • Sun J; Oncology Research, Amgen Inc., Thousand Oaks, CA 91320, USA.
  • Moriguchi J; Oncology Research, Amgen Inc., Thousand Oaks, CA 91320, USA.
  • Jun HT; MabVax Therapeutics Holdings, Inc., San Diego, CA 92121, USA.
  • Coxon A; Oncology Research, Amgen Inc., Thousand Oaks, CA 91320, USA.
  • Lee B; Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Room R814 BCM225, Houston, TX 77030, USA. Electronic address: blee@bcm.edu.
  • Kang Y; Department of Molecular Biology, Princeton University, Washington Road, LTL 255, Princeton, NJ 08544, USA; Cancer Metabolism and Growth Program, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA. Electronic address: ykang@princeton.edu.
Cancer Cell ; 32(6): 731-747.e6, 2017 Dec 11.
Article em En | MEDLINE | ID: mdl-29232552
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Proteína Jagged-1 / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Proteína Jagged-1 / Anticorpos Monoclonais / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos