Isothiazolinones are still widely used in paints purchased in five European countries: a follow-up study.
Contact Dermatitis
; 78(4): 246-253, 2018 Apr.
Article
em En
| MEDLINE
| ID: mdl-29265415
ABSTRACT
BACKGROUND:
An increasing incidence of contact allergy to methylisothiazolinone (MI) has been seen, caused, in particular, by cosmetic products and paints. A study from 2015 showed that 93.0% of paints bought in five European countries contained MI. New regulations have been discussed for paints in the EU, which may have influenced this market.OBJECTIVES:
To re-evaluate the use and concentrations of MI and four other isothiazolinones in water-based wall paints.METHODS:
Water-based white wall paints (n = 60) were purchased in retail stores in five European countries Denmark, France, Germany, Sweden, and the United Kingdom. The paints were analysed for isothiazolione content by the use of high-performance liquid chromatography coupled to ultraviolet detection, and the results were confirmed with high-performance liquid chromatography-tandem mass spectrometry.RESULTS:
MI was identified in 55 (91.7%) of the paints, with concentrations ranging from 1.1 to 142.7 ppm. The other isothiazolinones were identified in 20.0% [methylchloroisothiazolinone (MCI)] to 88.3% [benzisothiazolinone (BIT)] of the paints. BIT concentrations varied significantly between countries, whereas MI and MCI concentrations did not. There were no statistically significant differences in MI, MCI and BIT concentrations between the current study and the 2015 study.CONCLUSIONS:
MI and other isothiazolinones are widely used in paints available in Europe. Their use does not seem to be decreasing.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pintura
/
Tiazóis
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Cromatografia Líquida de Alta Pressão
/
Dermatite Alérgica de Contato
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Contact Dermatitis
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Dinamarca