Effects of autophagy on acid-sensing ion channel 1a-mediated apoptosis in rat articular chondrocytes.

Xie, Ya-Ya; Li, Yue; Zhou, Ren-Peng; Dai, Bei-Bei; Qian, Yue-Jiao; Wu, Xiao-Shan; Ge, Jin-Fang; Hu, Wei; Chen, Fei-Hu

Xie, Ya-Ya; Li, Yue; Zhou, Ren-Peng; Dai, Bei-Bei; Qian, Yue-Jiao; Wu, Xiao-Shan; Ge, Jin-Fang; Hu, Wei; Chen, Fei-Hu.

Afiliação

Xie YY; School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, People's Republic of China.
Li Y; School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, People's Republic of China.
Zhou RP; School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, People's Republic of China.
Dai BB; School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, People's Republic of China.
Qian YJ; School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, People's Republic of China.
Wu XS; School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, People's Republic of China.
Ge JF; School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, People's Republic of China.
Hu W; Department of Pharmacology, The Second Hospital of Anhui Medical University, Hefei, 230601, Anhui, People's Republic of China.
Chen FH; School of Pharmacy, Anhui Medical University, Meishan Road, Hefei, 230032, Anhui, People's Republic of China. cfhchina@sohu.com.

Mol Cell Biochem ; 443(1-2): 181-191, 2018 Jun.

Article em En | MEDLINE | ID: mdl-29273849

Assuntos

Canais Iônicos Sensíveis a Ácido/metabolismo; Apoptose; Autofagia; Cartilagem Articular/metabolismo; Condrócitos/metabolismo; Canais Iônicos Sensíveis a Ácido/genética; Animais; Artrite Reumatoide/genética; Artrite Reumatoide/metabolismo; Artrite Reumatoide/patologia; Proteína Beclina-1/genética; Proteína Beclina-1/metabolismo; Cartilagem Articular/patologia; Condrócitos/patologia; Técnicas de Silenciamento de Genes; Concentração de Íons de Hidrogênio; Masculino; Ratos; Ratos Sprague-Dawley

Palavras-chave

ASIC1a; Apoptosis; Autophagy; RA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Cartilagem Articular / Apoptose / Condrócitos / Canais Iônicos Sensíveis a Ácido Limite: Animals Idioma: En Revista: Mol Cell Biochem Ano de publicação: 2018 Tipo de documento: Article

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