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The possible repositioning of an oral anti-arthritic drug, auranofin, for Nrf2-activating therapy: The demonstration of Nrf2-dependent anti-oxidative action using a zebrafish model.
Fuse, Yuji; Endo, Yuka; Araoi, Sho; Daitoku, Hiroaki; Suzuki, Hiroyuki; Kato, Mitsuyasu; Kobayashi, Makoto.
Afiliação
  • Fuse Y; Department of Molecular and Developmental Biology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan; Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba 305-8575, Japan; Japan Society for the Promotion of Science
  • Endo Y; Department of Molecular and Developmental Biology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan; College of Biological Sciences, University of Tsukuba, Tsukuba 305-8575, Japan.
  • Araoi S; Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba 305-8577, Japan; Life Science Center, Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305-8577, Japan.
  • Daitoku H; Life Science Center, Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305-8577, Japan.
  • Suzuki H; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.
  • Kato M; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.
  • Kobayashi M; Department of Molecular and Developmental Biology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan. Electronic address: makobayash@md.tsukuba.ac.jp.
Free Radic Biol Med ; 115: 405-411, 2018 02 01.
Article em En | MEDLINE | ID: mdl-29277393
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite / Auranofina / Antirreumáticos / Proteínas de Peixe-Zebra / Fator 2 Relacionado a NF-E2 / Antioxidantes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Free Radic Biol Med Assunto da revista: BIOQUIMICA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite / Auranofina / Antirreumáticos / Proteínas de Peixe-Zebra / Fator 2 Relacionado a NF-E2 / Antioxidantes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Free Radic Biol Med Assunto da revista: BIOQUIMICA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article