One-Parameter Scaling Theory for DNA Extension in a Nanochannel.

Werner, E; Cheong, G K; Gupta, D; Dorfman, K D; Mehlig, B

Werner, E; Cheong, G K; Gupta, D; Dorfman, K D; Mehlig, B.

Afiliação

Werner E; Department of Physics, University of Gothenburg, SE-41296 Gothenburg, Sweden.
Cheong GK; Department of Chemical Engineering and Materials Science, University of Minnesota-Twin Cities, 421 Washington Avenue SE, Minneapolis, Minnesota 55455, USA.
Gupta D; Department of Chemical Engineering and Materials Science, University of Minnesota-Twin Cities, 421 Washington Avenue SE, Minneapolis, Minnesota 55455, USA.
Dorfman KD; Department of Chemical Engineering and Materials Science, University of Minnesota-Twin Cities, 421 Washington Avenue SE, Minneapolis, Minnesota 55455, USA.
Mehlig B; Department of Physics, University of Gothenburg, SE-41296 Gothenburg, Sweden.

Phys Rev Lett ; 119(26): 268102, 2017 Dec 29.

Article em En | MEDLINE | ID: mdl-29328690

ABSTRACT

ABSTRACT

Experiments measuring DNA extension in nanochannels are at odds with even the most basic predictions of current scaling arguments for the conformations of confined semiflexible polymers such as DNA. We show that a theory based on a weakly self-avoiding, one-dimensional "telegraph" process collapses experimental data and simulation results onto a single master curve throughout the experimentally relevant region of parameter space and explains the mechanisms at play.

Assuntos

DNA/química; Modelos Teóricos; Nanoestruturas; Modelos Moleculares; Nanotecnologia; Polímeros

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Nanoestruturas / Modelos Teóricos Tipo de estudo: Prognostic_studies Idioma: En Revista: Phys Rev Lett Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia

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