Prospective evaluation of EUS-guided fine needle biopsy in pancreatic mass lesions.
Endosc Int Open
; 6(2): E242-E248, 2018 Feb.
Article
em En
| MEDLINE
| ID: mdl-29423434
ABSTRACT
BACKGROUND AND STUDY AIM:
Due to the scarcity of specific data on endoscopic ultrasound (EUS)-guided fine-needle biopsies (SharkCore) FNB in the evaluation of pancreatic lesions, we performed a prospective study of the diagnostic performance of EUS SharkCore FNB in patients with pancreatic lesions. The aim of this study was to evaluate the diagnostic accuracy. PATIENTS ANDMETHODS:
Single-center prospective study of 41 consecutive patients referred for EUS-FNB from October 2015 to April 2016 at our center. EUS-FNB was obtained in a predefined setting regarding the procedure and pathological evaluation. Data regarding demographics, lesion, technical parameters, and diagnostic accuracy were obtained.RESULTS:
The study included 41 consecutive patients (22 males (54â%); median age 68 years). The average size of the lesions was 28âmm (median 30âmm). A diagnostic specimen was identified in 40 (98â%) cases during microscopy with an average of 2.4 passes. The route was trans-duodenal in 20 cases (49â%). The histological diagnosis of the specimens was malignant in 29 cases (71â%), benign in 8 (20â%), suspicious in 2 (5â%), atypical in 1 (2â%) and in 1 (2â%) no material for microscopic evaluation was obtained. This led to a diagnostic accuracy of 93â%, sensitivity of 91â% and a specificity of 100â%. 2 cases (5â%) of self-limiting bleeding were observed. The diagnosis at follow up was malignant in 32 (78â%) of the patients.CONCLUSIONS:
EUS-FNB of pancreatic mass lesions with the SharkCore needle produced specimens with a diagnostic accuracy of 93â%. The procedure was safe and easy to perform, and these data support the use of EUS-FNB in a routine setting.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Observational_studies
Idioma:
En
Revista:
Endosc Int Open
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Dinamarca