Glial fibrillary acidic protein antibody-positive meningoencephalomyelitis.
Pract Neurol
; 18(4): 315-319, 2018 Aug.
Article
em En
| MEDLINE
| ID: mdl-29440316
ABSTRACT
Glial fibrillary acidic protein antibody-positive meningoencephalomyelitis is a newly described, possibly under-recognised, severe inflammatory condition of the nervous system. The clinical presentation is variable but most commonly is a combination of meningitis, encephalitis and myelitis; other manifestations may include seizures, psychiatric symptoms and tremor. There is a significant association with malignancies, often occult, and with other autoimmune conditions. Although the disease responds well to corticosteroids acutely, it typically relapses when these are tapered, and so patients need long-term immunosuppression. We report a young man presenting with subacute meningoencephalitis and subsequent myelitis, and discuss the typical presentation and management of this severe but treatable condition.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteína Glial Fibrilar Ácida
/
Meningoencefalite
/
Anticorpos
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Mielite
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Humans
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Male
Idioma:
En
Revista:
Pract Neurol
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Reino Unido