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Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy.
Floros, Konstantinos V; Lochmann, Timothy L; Hu, Bin; Monterrubio, Carles; Hughes, Mark T; Wells, Jason D; Morales, Cristina Bernadó; Ghotra, Maninderjit S; Costa, Carlotta; Souers, Andrew J; Boikos, Sosipatros A; Leverson, Joel D; Tan, Ming; Serra, Violeta; Koblinski, Jennifer E; Arribas, Joaquin; Prat, Aleix; Paré, Laia; Miller, Todd W; Dozmorov, Mikhail G; Harada, Hisashi; Windle, Brad E; Scaltriti, Maurizio; Faber, Anthony C.
Afiliação
  • Floros KV; Department of Oral and Craniofacial Molecular Biology, Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298.
  • Lochmann TL; Department of Oral and Craniofacial Molecular Biology, Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298.
  • Hu B; Department of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA 23220.
  • Monterrubio C; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
  • Hughes MT; Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.
  • Wells JD; Department of Oral and Craniofacial Molecular Biology, Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298.
  • Morales CB; Department of Molecular & Systems Biology, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756.
  • Ghotra MS; Preclinical Research Program, Vall d'Hebron Institute of Oncology, 08035 Barcelona, Spain.
  • Costa C; Centro de Investigación Biomédica en Red en Oncologia (CIBERONC), 08035 Barcelona, Spain.
  • Souers AJ; Department of Oral and Craniofacial Molecular Biology, Philips Institute for Oral Health Research, VCU School of Dentistry and Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298.
  • Boikos SA; Department of Medicine, Massachusetts General Hospital, Cancer Center and Harvard Medical School, Boston, MA 02129.
  • Leverson JD; Oncology Discovery Department, AbbVie Inc., North Chicago, IL 60064.
  • Tan M; Division of Hematology, Oncology and Palliative Care, Virginia Commonwealth University, Massey Cancer Center, Richmond, VA 23298.
  • Serra V; Oncology Development Department, AbbVie Inc., North Chicago, IL 60064.
  • Koblinski JE; Department of Oncological Sciences, Mitchell Cancer Institute, University of South Alabama, Mobile, AL 36604.
  • Arribas J; Centro de Investigación Biomédica en Red en Oncologia (CIBERONC), 08035 Barcelona, Spain.
  • Prat A; Experimental Therapeutics Group, Vall d'Hebron Institute of Oncology, 08035 Barcelona, Spain.
  • Paré L; Department of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA 23220.
  • Miller TW; Preclinical Research Program, Vall d'Hebron Institute of Oncology, 08035 Barcelona, Spain.
  • Dozmorov MG; Centro de Investigación Biomédica en Red en Oncologia (CIBERONC), 08035 Barcelona, Spain.
  • Harada H; Institució Catalana de Recerca i Estudis Avançats, 08010 Barcelona, Spain.
  • Windle BE; Department of Biochemistry and Molecular Biology, Universitat Autónoma de Barcelona, Campus de la UAB, 08193 Bellaterra, Spain.
  • Scaltriti M; Translational Genomics and Targeted Therapeutics in Solid Tumors, Institut D'Investigacions Biomèdiques August Pi i Sunyer, 08036 Barcelona, Spain.
  • Faber AC; Translational Genomics and Targeted Therapeutics in Solid Tumors, Institut D'Investigacions Biomèdiques August Pi i Sunyer, 08036 Barcelona, Spain.
Proc Natl Acad Sci U S A ; 115(11): E2594-E2603, 2018 03 13.
Article em En | MEDLINE | ID: mdl-29476008
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Amplificação de Genes / Receptor ErbB-2 / Resistencia a Medicamentos Antineoplásicos / MicroRNAs Limite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Amplificação de Genes / Receptor ErbB-2 / Resistencia a Medicamentos Antineoplásicos / MicroRNAs Limite: Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article