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An optimized radiosynthesis of [18 F]FNDP, a positron emission tomography radiotracer for imaging soluble epoxide hydrolase (sEH).
Azad, Babak Behnam; Holt, Daniel P; Ravert, Hayden T; Horti, Andrew G; Dannals, Robert F.
Afiliação
  • Azad BB; Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Holt DP; Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Ravert HT; Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Horti AG; Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Dannals RF; Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
J Labelled Comp Radiopharm ; 61(7): 567-572, 2018 06 15.
Article em En | MEDLINE | ID: mdl-29529708
ABSTRACT
In this concise practitioner protocol, the radiochemical synthesis of [18 F]FNDP suitable for human positron emission tomography studies is described and the results from validation productions are presented. The high specific activity radiotracer product is prepared as a sterile, apyrogenic solution that conforms to current Good Manufacturing Practice requirements.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radioisótopos de Flúor / Niacinamida / Tomografia por Emissão de Pósitrons / Epóxido Hidrolases Tipo de estudo: Guideline Idioma: En Revista: J Labelled Comp Radiopharm Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radioisótopos de Flúor / Niacinamida / Tomografia por Emissão de Pósitrons / Epóxido Hidrolases Tipo de estudo: Guideline Idioma: En Revista: J Labelled Comp Radiopharm Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos