LV function validation of computer-assisted interventional system for cardiac resyncronisation therapy.
Int J Comput Assist Radiol Surg
; 13(6): 777-786, 2018 Jun.
Article
em En
| MEDLINE
| ID: mdl-29603064
ABSTRACT
PURPOSE:
Cardiac resynchronisation therapy (CRT) is an established treatment for symptomatic patients with heart failure, a prolonged QRS duration, and impaired left ventricular (LV) function; however, non-response rates remain high. Recently proposed computer-assisted interventional platforms for CRT provide new routes to improving outcomes. Interventional systems must process information in an accurate, fast and highly automated way that is easy for the interventional cardiologists to use. In this paper, an interventional CRT platform is validated against two offline diagnostic tools to demonstrate that accurate information processing is possible in the time critical interventional setting.METHODS:
The study consisted of 3 healthy volunteers and 16 patients with heart failure and conventional criteria for CRT. Data analysis included the calculation of end-diastolic volume, end-systolic volume, stroke volume and ejection fraction; computation of global volume over the cardiac cycle as well as time to maximal contraction expressed as a percentage of the total cardiac cycle.RESULTS:
The results showed excellent correlation ([Formula see text] values of [Formula see text] and Pearson correlation coefficient of [Formula see text]) with comparable offline diagnostic tools.CONCLUSION:
Results confirm that our interventional system has good accuracy in everyday clinical practice and can be of clinical utility in identification of CRT responders and LV function assessment.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Função Ventricular Esquerda
/
Imagem Cinética por Ressonância Magnética
/
Imageamento Tridimensional
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Cirurgia Assistida por Computador
/
Dispositivos de Terapia de Ressincronização Cardíaca
/
Insuficiência Cardíaca
/
Ventrículos do Coração
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Int J Comput Assist Radiol Surg
Assunto da revista:
RADIOLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Reino Unido