Antiproliferative and Antioxidant Activities of Wild Boletales Mushrooms from France.
Int J Med Mushrooms
; 20(1): 13-29, 2018.
Article
em En
| MEDLINE
| ID: mdl-29604910
ABSTRACT
We selected edible and inedible mushrooms growing in the Mediterranean area of France to screen their biological activity Caloboletus calopus, Rubroboletus lupinus, R. pulchrotinctus, R. satanas, Gyroporus castaneus, Suillus luteus, and Omphalotus olearius. Mushrooms were sequentially extracted using cyclohexane, chloroform, ethanol, and water. The antiproliferative activity against the HCT116 colon adenocarcinoma cell line and the antioxidant properties (DPPH radical scavenging assay, Folin-Ciocalteu assay, and oxygen radical absorbance capacity) of the Boletales extracts were evaluated and compared. Among the 28 mushroom extracts evaluated, 11 presented antiproliferative activity against HCT116 cells. These activities were not linked to antioxidant capacity. Among the antioxidant extracts, most were aqueous extracts in the oxygen radical absorbance capacity assay, whereas the highest values on the Folin-Ciocalteu and DPPH assays were noted for chloroform, ethanol, or aqueous extracts, depending on the mushroom species. Further studies are necessary to identify bioactive compounds and to valorize the mushrooms-for edible species, directly as health foods, or, for inedible mushrooms, as ingredients in the pharmaceutical and food industries.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Agaricales
/
Antioxidantes
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Int J Med Mushrooms
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
França