Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1.

Li, Wen; Tam, Ka Ming Vincent; Chan, Wai Wa Ray; Koon, Alex Chun; Ngo, Jacky Chi Ki; Chan, Ho Yin Edwin; Lau, Kwok-Fai

Li, Wen; Tam, Ka Ming Vincent; Chan, Wai Wa Ray; Koon, Alex Chun; Ngo, Jacky Chi Ki; Chan, Ho Yin Edwin; Lau, Kwok-Fai.

Afiliação

Li W; From the School of Life Sciences, Faculty of Science, Chinese University of Hong Kong, Shatin New Territories, Hong Kong.
Tam KMV; From the School of Life Sciences, Faculty of Science, Chinese University of Hong Kong, Shatin New Territories, Hong Kong.
Chan WWR; From the School of Life Sciences, Faculty of Science, Chinese University of Hong Kong, Shatin New Territories, Hong Kong.
Koon AC; From the School of Life Sciences, Faculty of Science, Chinese University of Hong Kong, Shatin New Territories, Hong Kong.
Ngo JCK; From the School of Life Sciences, Faculty of Science, Chinese University of Hong Kong, Shatin New Territories, Hong Kong.
Chan HYE; From the School of Life Sciences, Faculty of Science, Chinese University of Hong Kong, Shatin New Territories, Hong Kong.
Lau KF; From the School of Life Sciences, Faculty of Science, Chinese University of Hong Kong, Shatin New Territories, Hong Kong kflau@cuhk.edu.hk.

J Biol Chem ; 293(20): 7674-7688, 2018 05 18.

Article em En | MEDLINE | ID: mdl-29615491

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Proteínas do Tecido Nervoso/metabolismo; Neurogênese; Crescimento Neuronal/fisiologia; Neurônios/citologia; Proteínas Nucleares/metabolismo; Proteínas rac1 de Ligação ao GTP/metabolismo; Proteínas Adaptadoras de Transdução de Sinal/genética; Animais; Movimento Celular; Células Cultivadas; Humanos; Proteínas do Tecido Nervoso/genética; Neurônios/metabolismo; Proteínas Nucleares/genética; Ratos; Proteínas rac1 de Ligação ao GTP/genética

Palavras-chave

ADP-ribosylation factor (ARF); ELMO1; FE65; Ras-related C3 botulinum toxin substrate 1 (Rac1); amyloid precursor protein (APP); amyloid ß A4 precursor protein-binding family B member 1; guanine nucleotide exchange factor (GEF); neurite outgrowth

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Proteínas rac1 de Ligação ao GTP / Proteínas Adaptadoras de Transdução de Sinal / Neurogênese / Crescimento Neuronal / Proteínas do Tecido Nervoso / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Hong Kong

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