Tumor-Resident Dendritic Cells and Macrophages Modulate the Accumulation of TCR-Engineered T Cells in Melanoma.

Hotblack, Alastair; Holler, Angelika; Piapi, Alice; Ward, Sophie; Stauss, Hans J; Bennett, Clare L

Hotblack, Alastair; Holler, Angelika; Piapi, Alice; Ward, Sophie; Stauss, Hans J; Bennett, Clare L.

Afiliação

Hotblack A; Institute for Immunity and Transplantation, Division of Infection and Immunity, University College London, London NW3 2PF, UK.
Holler A; Institute for Immunity and Transplantation, Division of Infection and Immunity, University College London, London NW3 2PF, UK.
Piapi A; Institute for Immunity and Transplantation, Division of Infection and Immunity, University College London, London NW3 2PF, UK.
Ward S; Institute for Immunity and Transplantation, Division of Infection and Immunity, University College London, London NW3 2PF, UK; Cancer Institute, Division of Cancer Studies, University College London, London WC1E 6DD, UK.
Stauss HJ; Institute for Immunity and Transplantation, Division of Infection and Immunity, University College London, London NW3 2PF, UK. Electronic address: h.stauss@ucl.ac.uk.
Bennett CL; Institute for Immunity and Transplantation, Division of Infection and Immunity, University College London, London NW3 2PF, UK; Cancer Institute, Division of Cancer Studies, University College London, London WC1E 6DD, UK. Electronic address: c.bennett@ucl.ac.uk.

Mol Ther ; 26(6): 1471-1481, 2018 06 06.

Article em En | MEDLINE | ID: mdl-29628306

Assuntos

Células Dendríticas/metabolismo; Macrófagos/metabolismo; Receptores de Antígenos de Linfócitos T/metabolismo; Animais; Antígenos de Neoplasias/imunologia; Antígenos de Neoplasias/metabolismo; Antígeno CD11c/imunologia; Antígeno CD11c/metabolismo; Fator de Crescimento Semelhante a EGF de Ligação à Heparina/imunologia; Fator de Crescimento Semelhante a EGF de Ligação à Heparina/metabolismo; Humanos; Imunoterapia Adotiva/métodos; Melanoma Experimental/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Receptores de Antígenos de Linfócitos T/imunologia

Palavras-chave

adoptive cellular therapy; dendritic cells; engineered T cells; myeloid cells; tumor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Receptores de Antígenos de Linfócitos T / Macrófagos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

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