Bipedal hopping timed to a metronome to detect impairments in anticipatory motor control in people with mild multiple sclerosis.
Clin Biomech (Bristol, Avon)
; 55: 45-52, 2018 06.
Article
em En
| MEDLINE
| ID: mdl-29684789
ABSTRACT
BACKGROUND:
People with mild multiple sclerosis (MS) often report subtle deficits in balance and cognition but display no measurable impairment on clinical assessments. We examined whether hopping to a metronome beat had the potential to detect anticipatory motor control deficits among people with mild MS (Expanded Disability Status Scaleâ¯≤â¯3.5).METHODS:
Participants with MS (nâ¯=â¯13), matched controls (nâ¯=â¯9), and elderly subjects (nâ¯=â¯13) completed tests of cognition (Montreal Cognitive Assessment (MoCA)) and motor performance (Timed 25 Foot Walk Test (T25FWT)). Participants performed two bipedal hopping tasks at 40 beats/min (bpm) and 60-bpm in random order. Hop characteristics (length, symmetry, variability) and delay from the metronome beat were extracted from an instrumented walkway and compared between groups.RESULTS:
The MS group became more delayed from the metronome beat over time whereas elderly subjects tended to hop closer to the beat (Fâ¯=â¯4.52, pâ¯=â¯0.02). Delay of the first hop during 60-bpm predicted cognition in people with MS (Râ¯=â¯0.55, ßâ¯=â¯4.64 (SD 4.63), Fâ¯=â¯4.85, pâ¯=â¯0.05) but not among control (Râ¯=â¯0.07, pâ¯=â¯0.86) or elderly subjects (Râ¯=â¯0.17, pâ¯=â¯0.57). In terms of hopping characteristics, at 60-bpm, people with MS and matched controls were significantly different from the elderly group. However, at 40-bpm, the MS group was no longer significantly different from the elderly group, even though matched controls and elderly still differed significantly.CONCLUSIONS:
This new timed hopping test may be able to detect both physical ability, and feed-forward anticipatory control impairments in people with mild MS. Hopping at a frequency of 40-bpm seemed more challenging. Several aspects of anticipatory motor control can be measured including reaction time to the first metronome cue and the ability to adapt and anticipate the beat over time.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos das Habilidades Motoras
/
Teste de Esforço
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Antecipação Psicológica
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Esclerose Múltipla
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Clin Biomech (Bristol, Avon)
Assunto da revista:
ENGENHARIA BIOMEDICA
/
FISIOLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Canadá