RANGER-DTL 2.0: rigorous reconstruction of gene-family evolution by duplication, transfer and loss.
Bioinformatics
; 34(18): 3214-3216, 2018 09 15.
Article
em En
| MEDLINE
| ID: mdl-29688310
ABSTRACT
Summary:
RANGER-DTL 2.0 is a software program for inferring gene family evolution using Duplication-Transfer-Loss reconciliation. This new software is highly scalable and easy to use, and offers many new features not currently available in any other reconciliation program. RANGER-DTL 2.0 has a particular focus on reconciliation accuracy and can account for many sources of reconciliation uncertainty including uncertain gene tree rooting, gene tree topological uncertainty, multiple optimal reconciliations and alternative event cost assignments. RANGER-DTL 2.0 is open-source and written in C++ and Python. Availability and implementation Pre-compiled executables, source code (open-source under GNU GPL) and a detailed manual are freely available from http//compbio.engr.uconn.edu/software/RANGER-DTL/. Supplementary information Supplementary data are available at Bioinformatics online.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
Evolução Molecular
/
Biologia Computacional
/
Duplicação Gênica
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos