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Clinical Course of Nodular Regenerative Hyperplasia in Thiopurine Treated Inflammatory Bowel Disease Patients.
Simsek, Melek; Meijer, Berrie; Ramsoekh, Dewkoemar; Bouma, Gerd; van der Wouden, Egbert-Jan; den Hartog, Bert; de Vries, Annemarie C; Hoentjen, Frank; Dijkstra, Gerard; de Boer, Sybrand Y; Jansen, Jeroen M; van der Meulen, Andrea E; Beukers, Ruud; Brink, Menno A; Steinhauser, Toos; Oldenburg, Bas; Gilissen, Lennard P; Naber, Ton H; Verhagen, Marc A; de Boer, Nanne K H; Mulder, Chris J J.
Afiliação
  • Simsek M; Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: m.simsek@vumc.nl.
  • Meijer B; Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
  • Ramsoekh D; Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
  • Bouma G; Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
  • van der Wouden EJ; Department of Gastroenterology and Hepatology, Isala Clinics, Zwolle, The Netherlands.
  • den Hartog B; Department of Gastroenterology and Hepatology, Rijnstate Hospital, Arnhem, The Netherlands.
  • de Vries AC; Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Hoentjen F; Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Dijkstra G; Department of Gastroenterology and Hepatology, University Medical Center and University of Groningen, Groningen, The Netherlands.
  • de Boer SY; Department of Gastroenterology and Hepatology, Slingeland Hospital, Doetinchem, The Netherlands.
  • Jansen JM; Department of Gastroenterology and Hepatology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
  • van der Meulen AE; Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Beukers R; Department of Gastroenterology and Hepatology, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
  • Brink MA; Department of Gastroenterology and Hepatology, Meander Medical Center, Amersfoort, The Netherlands.
  • Steinhauser T; Department of Gastroenterology and Hepatology, Bravis Hospital, Roosendaal, The Netherlands.
  • Oldenburg B; Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Gilissen LP; Department of Gastroenterology and Hepatology, Catharina Hospital, Eindhoven, The Netherlands.
  • Naber TH; Department of Gastroenterology and Hepatology, Tergooi Hospital, Hilversum, The Netherlands.
  • Verhagen MA; Department of Gastroenterology and Hepatology, Diakonessen Hospital, Utrecht, The Netherlands.
  • de Boer NKH; Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
  • Mulder CJJ; Department of Gastroenterology and Hepatology, VU University Medical Center, Amsterdam, The Netherlands.
Clin Gastroenterol Hepatol ; 17(3): 568-570, 2019 02.
Article em En | MEDLINE | ID: mdl-29775790
ABSTRACT
Nodular regenerative hyperplasia (NRH) is a poorly understood liver condition, which is increasingly recognized in thiopurine-treated patients with inflammatory bowel disease (IBD).1 It is difficult to establish an optimal approach to NRH patients, because its manifestations are highly variable (from asymptomatic to symptoms of noncirrhotic portal hypertension [NCPH]) and the prognosis is unknown.2 The aim of this study was to identify NRH cases in IBD patients treated with azathioprine, mercaptopurine, and/or thioguanine, and to describe its clinical course.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azatioprina / Tioguanina / Doenças Inflamatórias Intestinais / Hiperplasia / Hepatopatias / Mercaptopurina Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Gastroenterol Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Azatioprina / Tioguanina / Doenças Inflamatórias Intestinais / Hiperplasia / Hepatopatias / Mercaptopurina Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Gastroenterol Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2019 Tipo de documento: Article