Fostering translation of genetics research: an NIDDK perspective.
Per Med
; 6(5): 579-588, 2009 Sep.
Article
em En
| MEDLINE
| ID: mdl-29783302
ABSTRACT
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the NIH, supports a large and varied portfolio of genetic research grants and contracts. As a funding agency, the NIDDK aims to support research that can be translated into discoveries that help to reduce the burden of genetic diseases. Except for the major advances in diagnostics for Mendelian diseases and a few disease-specific therapies, there has only been modest clinical benefit from the investment in human genetics research. For genetically complex, multifactorial diseases, including many of the common diseases in the USA, the risk genes are harder to find than for Mendelian diseases, and translation seems even further off. How can NIDDK make its investment in human genetics research pay off? This report describes the challenges in human genetics research and NIDDK's fivefold funding strategy to support science that will eventually lead to meaningful translation.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Per Med
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
Estados Unidos