Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid.

Zakeyah, A A; Whitt, J; Duke, C; Gilmore, D F; Meeker, D G; Smeltzer, M S; Alam, M A

Zakeyah, A A; Whitt, J; Duke, C; Gilmore, D F; Meeker, D G; Smeltzer, M S; Alam, M A.

Afiliação

Zakeyah AA; Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, United States.
Whitt J; Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, United States.
Duke C; Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, United States.
Gilmore DF; Department of Biological Sciences, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, United States.
Meeker DG; Department of Microbiology and Immunology, College of Medicine, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, United States.
Smeltzer MS; Department of Microbiology and Immunology, College of Medicine, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, United States.
Alam MA; Department of Chemistry and Physics, College of Science and Mathematics, Arkansas State University, Jonesboro, AR 72467, United States. Electronic address: malam@astate.edu.

Bioorg Med Chem Lett ; 28(17): 2914-2919, 2018 09 15.

Article em En | MEDLINE | ID: mdl-30017319

Assuntos

Acinetobacter baumannii/efeitos dos fármacos; Antibacterianos/farmacologia; Bacillus subtilis/efeitos dos fármacos; Benzoatos/farmacologia; Hidrazonas/farmacologia; Staphylococcus aureus/efeitos dos fármacos; Antibacterianos/síntese química; Antibacterianos/química; Benzoatos/síntese química; Benzoatos/química; Relação Dose-Resposta a Droga; Hidrazonas/síntese química; Hidrazonas/química; Testes de Sensibilidade Microbiana; Estrutura Molecular; Relação Estrutura-Atividade

Palavras-chave

Acinetobacter baumannii; Antimicrobial; Hydrazone; MRSA; Pyrazole

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Bacillus subtilis / Benzoatos / Acinetobacter baumannii / Hidrazonas / Antibacterianos Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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