Contact inhibition controls cell survival and proliferation via YAP/TAZ-autophagy axis.

Pavel, Mariana; Renna, Maurizio; Park, So Jung; Menzies, Fiona M; Ricketts, Thomas; Füllgrabe, Jens; Ashkenazi, Avraham; Frake, Rebecca A; Lombarte, Alejandro Carnicer; Bento, Carla F; Franze, Kristian; Rubinsztein, David C

Pavel, Mariana; Renna, Maurizio; Park, So Jung; Menzies, Fiona M; Ricketts, Thomas; Füllgrabe, Jens; Ashkenazi, Avraham; Frake, Rebecca A; Lombarte, Alejandro Carnicer; Bento, Carla F; Franze, Kristian; Rubinsztein, David C.

Afiliação

Pavel M; Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.
Renna M; Department of Immunology, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi, 700115, Romania.
Park SJ; Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.
Menzies FM; Department of Molecular Medicine and Medical Biotechnology, University of Naples "Federico II", Naples, 80131, Italy.
Ricketts T; Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.
Füllgrabe J; Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.
Ashkenazi A; Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.
Frake RA; Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.
Lombarte AC; Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.
Bento CF; Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.
Franze K; Department of Physiology Development and Neuroscience, University of Cambridge, CB2 3DY, Cambridge, UK.
Rubinsztein DC; Department of Medical Genetics, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0XY, UK.

Nat Commun ; 9(1): 2961, 2018 07 27.

Article em En | MEDLINE | ID: mdl-30054475

Assuntos

Proteínas Adaptadoras de Transdução de Sinal/metabolismo; Autofagia/fisiologia; Proliferação de Células; Inibição de Contato/fisiologia; Fosfoproteínas/metabolismo; Fatores de Transcrição/metabolismo; Citoesqueleto de Actina/metabolismo; Actinas/metabolismo; Aciltransferases; Proteínas Adaptadoras de Transdução de Sinal/genética; Animais; Apoptose; Autofagossomos/metabolismo; Proteína de Capeamento de Actina CapZ/metabolismo; Contagem de Células; Linhagem Celular Tumoral; Sobrevivência Celular; Células Epiteliais; Matriz Extracelular/metabolismo; Fibroblastos; Técnicas de Silenciamento de Genes; Glucose; Células HeLa; Humanos; Hipóxia; Camundongos; Miosina Tipo II/genética; Fosfoproteínas/genética; Transdução de Sinais; Fatores de Transcrição/genética; Proteínas de Sinalização YAP

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Autofagia / Fatores de Transcrição / Inibição de Contato / Proteínas Adaptadoras de Transdução de Sinal / Proliferação de Células Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido

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