Primary oral etoposide therapy in gestational trophoblastic disease. An update.
Cancer
; 58(1): 14-7, 1986 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-3011237
ABSTRACT
Sixty patients who developed persistent or metastatic gestational trophoblastic disease (GTD) received primary oral etoposide therapy (VP 16-213). Twelve patients had metastatic GTD. Fifty-nine patients achieved biochemical remission. One patient had marked nausea and vomiting and the therapy was switched to a methotrexate/folinic acid regimen. Three patients developed relapse of GTD, giving a relapse rate of 5.1%. Etoposide is an active drug against choriocarcinoma. Its use should not be restricted to drug-resistant GTD.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Podofilotoxina
/
Neoplasias Uterinas
/
Neoplasias Trofoblásticas
/
Etoposídeo
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Cancer
Ano de publicação:
1986
Tipo de documento:
Article