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Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma.
Kondrashova, Olga; Topp, Monique; Nesic, Ksenija; Lieschke, Elizabeth; Ho, Gwo-Yaw; Harrell, Maria I; Zapparoli, Giada V; Hadley, Alison; Holian, Robert; Boehm, Emma; Heong, Valerie; Sanij, Elaine; Pearson, Richard B; Krais, John J; Johnson, Neil; McNally, Orla; Ananda, Sumitra; Alsop, Kathryn; Hutt, Karla J; Kaufmann, Scott H; Lin, Kevin K; Harding, Thomas C; Traficante, Nadia; deFazio, Anna; McNeish, Iain A; Bowtell, David D; Swisher, Elizabeth M; Dobrovic, Alexander; Wakefield, Matthew J; Scott, Clare L.
Afiliação
  • Kondrashova O; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • Topp M; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Nesic K; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • Lieschke E; Department of Medicine and Health Sciences, Monash University, Clayton, VIC, 3168, Australia.
  • Ho GY; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • Harrell MI; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Zapparoli GV; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • Hadley A; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • Holian R; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Boehm E; Royal Women's Hospital, Parkville, VIC, 3052, Australia.
  • Heong V; Research Division, Peter MacCallum Cancer Centre, Grattan Street, Parkville, VIC, 3010, Australia.
  • Sanij E; Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, 98195, USA.
  • Pearson RB; Olivia Newton-John Cancer Research Institute, Heidelberg, VIC, 3084, Australia.
  • Krais JJ; School of Cancer Medicine, La Trobe University, Bundoora, VIC, 3086, Australia.
  • Johnson N; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • McNally O; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Ananda S; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • Alsop K; School of Medicine, University of Melbourne, Parkville, VIC, 3052, Australia.
  • Hutt KJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • Kaufmann SH; School of Medicine, University of Melbourne, Parkville, VIC, 3052, Australia.
  • Lin KK; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
  • Harding TC; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Traficante N; Royal Women's Hospital, Parkville, VIC, 3052, Australia.
  • deFazio A; Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, 3010, Australia.
  • McNeish IA; Research Division, Peter MacCallum Cancer Centre, Grattan Street, Parkville, VIC, 3010, Australia.
  • Bowtell DD; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, 3010, Australia.
  • Swisher EM; Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, VIC, 3010, Australia.
  • Dobrovic A; Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, 3168, Australia.
  • Wakefield MJ; Fox Chase Cancer Centre, Philadelphia, PA, 19111, USA.
  • Scott CL; Fox Chase Cancer Centre, Philadelphia, PA, 19111, USA.
Nat Commun ; 9(1): 3970, 2018 09 28.
Article em En | MEDLINE | ID: mdl-30266954
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteína BRCA1 / Metilação de DNA / Ensaios Antitumorais Modelo de Xenoenxerto / Inibidores de Poli(ADP-Ribose) Polimerases / Indóis Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteína BRCA1 / Metilação de DNA / Ensaios Antitumorais Modelo de Xenoenxerto / Inibidores de Poli(ADP-Ribose) Polimerases / Indóis Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Austrália