Active Tuberculosis Is Characterized by Highly Differentiated Effector Memory Th1 Cells.

Arrigucci, Riccardo; Lakehal, Karim; Vir, Pooja; Handler, Deborah; Davidow, Amy L; Herrera, Rosa; Estrada-Guzmán, Julia Dolores; Bushkin, Yuri; Tyagi, Sanjay; Lardizabal, Alfred A; Gennaro, Maria Laura

Arrigucci, Riccardo; Lakehal, Karim; Vir, Pooja; Handler, Deborah; Davidow, Amy L; Herrera, Rosa; Estrada-Guzmán, Julia Dolores; Bushkin, Yuri; Tyagi, Sanjay; Lardizabal, Alfred A; Gennaro, Maria Laura.

Afiliação

Arrigucci R; Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Lakehal K; Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Vir P; Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Handler D; Global Tuberculosis Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Davidow AL; Department of Biostatistics, School of Public Health, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Herrera R; Facultad de Medicina Mexicali, Universidad Autónoma de Baja California, Mexicali, Mexico.
Estrada-Guzmán JD; Facultad de Medicina Mexicali, Universidad Autónoma de Baja California, Mexicali, Mexico.
Bushkin Y; Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Tyagi S; Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Lardizabal AA; Global Tuberculosis Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Gennaro ML; Public Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.

Front Immunol ; 9: 2127, 2018.

Article em En | MEDLINE | ID: mdl-30283456

Assuntos

Diferenciação Celular/imunologia; Memória Imunológica/imunologia; Tuberculose Latente/imunologia; Células Th1/imunologia; Tuberculose/imunologia; Adulto; Idoso; Linfócitos T CD4-Positivos/imunologia; Linfócitos T CD4-Positivos/metabolismo; Células Cultivadas; Feminino; Humanos; Testes Imunológicos; Interferon gama/genética; Interferon gama/imunologia; Interferon gama/metabolismo; Tuberculose Latente/diagnóstico; Tuberculose Latente/microbiologia; Masculino; Pessoa de Meia-Idade; Mycobacterium tuberculosis/imunologia; Mycobacterium tuberculosis/fisiologia; Células Th1/metabolismo; Tuberculose/diagnóstico; Tuberculose/microbiologia; Fator de Necrose Tumoral alfa/genética; Fator de Necrose Tumoral alfa/imunologia; Fator de Necrose Tumoral alfa/metabolismo; Adulto Jovem

Palavras-chave

FISH-Flow; T cell activation; cytokine; flow cytometry; immunophenotyping; memory T cells; single-cell gene expression

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tuberculose / Diferenciação Celular / Células Th1 / Tuberculose Latente / Memória Imunológica Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Front Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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