Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin-antitoxin system: targeting a tRNase to tackle mycobacterial adaptation.

Deep, Amar; Tiwari, Prabhakar; Agarwal, Sakshi; Kaundal, Soni; Kidwai, Saqib; Singh, Ramandeep; Thakur, Krishan G

Deep, Amar; Tiwari, Prabhakar; Agarwal, Sakshi; Kaundal, Soni; Kidwai, Saqib; Singh, Ramandeep; Thakur, Krishan G.

Afiliação

Deep A; Structural Biology Laboratory, G. N. Ramachandran Protein Centre, Council of Scientific and Industrial Research-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh 160036, India.
Tiwari P; Tuberculosis Research Laboratory, Vaccine and Infectious Disease Research Centre, Translational Health Science and Technology Institute, NCR-Biotech Science Cluster, 3rd Milestone, Faridabad Gurgaon Expressway, Faridabad 121001, India.
Agarwal S; Tuberculosis Research Laboratory, Vaccine and Infectious Disease Research Centre, Translational Health Science and Technology Institute, NCR-Biotech Science Cluster, 3rd Milestone, Faridabad Gurgaon Expressway, Faridabad 121001, India.
Kaundal S; Structural Biology Laboratory, G. N. Ramachandran Protein Centre, Council of Scientific and Industrial Research-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh 160036, India.
Kidwai S; Tuberculosis Research Laboratory, Vaccine and Infectious Disease Research Centre, Translational Health Science and Technology Institute, NCR-Biotech Science Cluster, 3rd Milestone, Faridabad Gurgaon Expressway, Faridabad 121001, India.
Singh R; Tuberculosis Research Laboratory, Vaccine and Infectious Disease Research Centre, Translational Health Science and Technology Institute, NCR-Biotech Science Cluster, 3rd Milestone, Faridabad Gurgaon Expressway, Faridabad 121001, India.
Thakur KG; Structural Biology Laboratory, G. N. Ramachandran Protein Centre, Council of Scientific and Industrial Research-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh 160036, India.

Nucleic Acids Res ; 46(21): 11639-11655, 2018 11 30.

Article em En | MEDLINE | ID: mdl-30329074

Assuntos

Proteínas de Bactérias/metabolismo; Mycobacterium bovis/genética; Mycobacterium bovis/metabolismo; Sistemas Toxina-Antitoxina/genética; Animais; Proteínas de Bactérias/genética; Toxinas Bacterianas/metabolismo; Sítios de Ligação; Domínio Catalítico; Cristalografia por Raios X; Feminino; Cobaias; Cinética; Modelos Moleculares; Simulação de Acoplamento Molecular; Mycobacterium smegmatis/metabolismo; Mycobacterium tuberculosis/metabolismo; Ribonucleases/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Sistemas Toxina-Antitoxina / Mycobacterium bovis Limite: Animals Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia

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