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Induction chemotherapy (IC) followed by radiotherapy (RT) versus cetuximab plus IC and RT in advanced laryngeal/hypopharyngeal cancer resectable only by total laryngectomy-final results of the larynx organ preservation trial DeLOS-II.
Dietz, A; Wichmann, G; Kuhnt, T; Pfreundner, L; Hagen, R; Scheich, M; Kölbl, O; Hautmann, M G; Strutz, J; Schreiber, F; Bockmühl, U; Schilling, V; Feyer, P; de Wit, M; Maschmeyer, G; Jungehülsing, M; Schroeder, U; Wollenberg, B; Sittel, C; Münter, M; Lenarz, T; Klussmann, J P; Guntinas-Lichius, O; Rudack, C; Eich, H T; Foerg, T; Preyer, S; Westhofen, M; Welkoborsky, H J; Esser, D; Thurnher, D; Remmert, S; Sudhoff, H; Görner, M; Bünzel, J; Budach, V; Held, S; Knödler, M; Lordick, F; Wiegand, S; Vogel, K; Boehm, A; Flentje, M; Keilholz, U.
Afiliação
  • Dietz A; Department of Otolaryngology, Head and Neck Surgery, University Leipzig, Leipzig, Germany. Electronic address: Andreas.Dietz@medizin.uni-leipzig.de.
  • Wichmann G; Department of Otolaryngology, Head and Neck Surgery, University Leipzig, Leipzig, Germany.
  • Kuhnt T; Department of Radiation Oncology, University Leipzig, Leipzig, Germany.
  • Pfreundner L; Department of Radiation Oncology, University Würzburg, Würzburg, Germany.
  • Hagen R; Department of Otolaryngology, Head and Neck Surgery, University Würzburg, Würzburg, Germany.
  • Scheich M; Department of Otolaryngology, Head and Neck Surgery, University Würzburg, Würzburg, Germany.
  • Kölbl O; Department of Radiation Oncology, University Regensburg, Regensburg, Germany.
  • Hautmann MG; Department of Radiation Oncology, University Regensburg, Regensburg, Germany.
  • Strutz J; Department of Otolaryngology, Head and Neck Surgery, University Regensburg, Regensburg, Germany.
  • Schreiber F; Department of Otolaryngology, Head and Neck Surgery, Klinikum Kassel, Kassel, Germany.
  • Bockmühl U; Department of Otolaryngology, Head and Neck Surgery, Klinikum Kassel, Kassel, Germany.
  • Schilling V; Department of Otolaryngology, Head and Neck Surgery, Vivantes, Berlin, Neukölln, Germany.
  • Feyer P; Department of Radiation Oncology, Vivantes, Berlin, Neukölln, Germany.
  • de Wit M; Department of Hemato-Oncology, Vivantes, Berlin, Neukölln, Germany.
  • Maschmeyer G; Department of Hematology, Oncology and Palliative Care, Klinikum Ernst von Bergmann, Potsdam, Germany.
  • Jungehülsing M; Department of Otolaryngology, Head and Neck Surgery, Potsdam Klinikum, Potsdam, Germany.
  • Schroeder U; Department of Otolaryngology, Head and Neck Surgery, University Lübeck, Lübeck, Germany.
  • Wollenberg B; Department of Otolaryngology, Head and Neck Surgery, University Lübeck, Lübeck, Germany.
  • Sittel C; Department of Otolaryngology, Head and Neck Surgery, Katharinen Hospital, Stuttgart, Germany.
  • Münter M; Department of Radiation Oncology, Katharinen Hospital, Stuttgart, Germany.
  • Lenarz T; Department of Otolaryngology, Head and Neck Surgery, MHH Hannover, Hannover, Germany.
  • Klussmann JP; Department of Otolaryngology, Head and Neck Surgery, University Gießen, Gießen, Germany.
  • Guntinas-Lichius O; Department of Otolaryngology, Head and Neck Surgery, Jena University Hospital, Jena, Germany.
  • Rudack C; Department of Otolaryngology, Head and Neck Surgery, University Münster, Münster, Germany.
  • Eich HT; Department of Radiation Oncology, University Münster, Münster, Germany.
  • Foerg T; Department of Radiation Oncology, Head and Neck Surgery, St. Vincentius, ViDia Christliche Kliniken Karlsruhe, Karlsruhe, Germany.
  • Preyer S; Department of Otolaryngology, Head and Neck Surgery, St. Vincentius, ViDia Christliche Kliniken Karlsruhe, Karlsruhe, Germany.
  • Westhofen M; Department of Otolaryngology, Head and Neck Surgery, University Aachen, Aachen, Germany.
  • Welkoborsky HJ; Department of Otolaryngology, Head and Neck Surgery, Klinikum Nordstadt, Hannover, Germany.
  • Esser D; Department of Otolaryngology, Head and Neck Surgery, Helios Klinikum, Erfurt, Germany.
  • Thurnher D; Department of Otolaryngology, Head and Neck Surgery, University Graz, Graz, Austria.
  • Remmert S; Department of Otolaryngology, Head and Neck Surgery, Malteser Hospital Duisburg, Duisburg, Germany.
  • Sudhoff H; Department of Otolaryngology, Head and Neck Surgery, Klinikum Bielefeld, Bielefeld, Germany.
  • Görner M; Department of Hemato-Oncology, Klinikum Bielefeld, Bielefeld, Germany.
  • Bünzel J; Department of Otolaryngology, Head and Neck Surgery, Klinikum Nordhausen, Nordhausen, Germany.
  • Budach V; Department of Radiation Oncology, CCC, Charité-University Medicine, Berlin, Germany.
  • Held S; ClinAssess GmbH, Leverkusen, Germany.
  • Knödler M; Department of Oncology, University Cancer Center Leipzig (UCCL), Leipzig, Germany.
  • Lordick F; Department of Oncology, University Cancer Center Leipzig (UCCL), Leipzig, Germany.
  • Wiegand S; Department of Otolaryngology, Head and Neck Surgery, University Leipzig, Leipzig, Germany.
  • Vogel K; Department of Otolaryngology, Head and Neck Surgery, University Leipzig, Leipzig, Germany.
  • Boehm A; Department of Otolaryngology, Head and Neck Surgery, St. Georg Hospital Leipzig, Leipzig, Germany.
  • Flentje M; Department of Radiation Oncology, University Würzburg, Würzburg, Germany.
  • Keilholz U; Charité Comprehensive Cancer Center, Berlin, Germany.
Ann Oncol ; 29(10): 2105-2114, 2018 10 01.
Article em En | MEDLINE | ID: mdl-30412221
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radioterapia / Protocolos de Quimioterapia Combinada Antineoplásica / Neoplasias Hipofaríngeas / Neoplasias Laríngeas / Terapia de Salvação / Quimiorradioterapia / Laringectomia Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radioterapia / Protocolos de Quimioterapia Combinada Antineoplásica / Neoplasias Hipofaríngeas / Neoplasias Laríngeas / Terapia de Salvação / Quimiorradioterapia / Laringectomia Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article