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Target (MexB)- and Efflux-Based Mechanisms Decreasing the Effectiveness of the Efflux Pump Inhibitor D13-9001 in Pseudomonas aeruginosa PAO1: Uncovering a New Role for MexMN-OprM in Efflux of ß-Lactams and a Novel Regulatory Circuit (MmnRS) Controlling MexMN Expression.
Ranjitkar, Srijan; Jones, Adriana K; Mostafavi, Mina; Zwirko, Zachary; Iartchouk, Oleg; Barnes, S Whitney; Walker, John R; Willis, Thomas W; Lee, Patrick S; Dean, Charles R.
Afiliação
  • Ranjitkar S; Infectious Diseases, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
  • Jones AK; Infectious Diseases, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
  • Mostafavi M; Infectious Diseases, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
  • Zwirko Z; Biotherapeutic and Analytical Technologies, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Iartchouk O; Biotherapeutic and Analytical Technologies, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA.
  • Barnes SW; Genomics Institute of Novartis Research Foundation (GNF), San Diego, California, USA.
  • Walker JR; Genomics Institute of Novartis Research Foundation (GNF), San Diego, California, USA.
  • Willis TW; Infectious Diseases, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
  • Lee PS; Infectious Diseases, Novartis Institutes for Biomedical Research, Emeryville, California, USA.
  • Dean CR; Infectious Diseases, Novartis Institutes for Biomedical Research, Emeryville, California, USA charlesr.dean@novartis.com.
Antimicrob Agents Chemother ; 63(2)2019 02.
Article em En | MEDLINE | ID: mdl-30420483
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Pseudomonas aeruginosa / Beta-Lactamas / Compostos de Amônio Quaternário Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Piperidinas / Pseudomonas aeruginosa / Beta-Lactamas / Compostos de Amônio Quaternário Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos