The Need for Speed: Run-On Oligomer Filament Formation Provides Maximum Speed with Maximum Sequestration of Activity.

Barahona, Claudia J; Basantes, L Emilia; Tompkins, Kassidy J; Heitman, Desirae M; Chukwu, Barbara I; Sanchez, Juan; Sanchez, Jonathan L; Ghadirian, Niloofar; Park, Chad K; Horton, N C

Barahona, Claudia J; Basantes, L Emilia; Tompkins, Kassidy J; Heitman, Desirae M; Chukwu, Barbara I; Sanchez, Juan; Sanchez, Jonathan L; Ghadirian, Niloofar; Park, Chad K; Horton, N C.

Afiliação

Barahona CJ; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Basantes LE; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Tompkins KJ; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Heitman DM; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Chukwu BI; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Sanchez J; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Sanchez JL; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Ghadirian N; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Park CK; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Horton NC; Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA nhorton@u.arizona.edu.

J Virol ; 93(5)2019 03 01.

Article em En | MEDLINE | ID: mdl-30518649

Assuntos

Bacteriófagos/genética; DNA Viral/metabolismo; Desoxirribonucleases de Sítio Específico do Tipo II/metabolismo; Streptomyces griseus/virologia; Bacteriófagos/crescimento & desenvolvimento; Sequência de Bases/genética; DNA Viral/genética; Desoxirribonucleases de Sítio Específico do Tipo II/genética; Ativação Enzimática; Streptomyces griseus/genética; Relação Estrutura-Atividade; Especificidade por Substrato

Palavras-chave

antiphage mechanism; enzyme kinetics; enzyme mechanism; filament forming enzymes; kinetic simulations; phage infection; protein structure-function; restriction endonuclease

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptomyces griseus / Bacteriófagos / DNA Viral / Desoxirribonucleases de Sítio Específico do Tipo II Idioma: En Revista: J Virol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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