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Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor.
Li, Yali; Huang, Taomin; Lou, Bin; Ye, Deyong; Qi, Xiangyu; Li, Xiaoxia; Hu, Shuang; Ding, Tingbo; Chen, Yan; Cao, Yang; Mo, Mingguang; Dong, Jibin; Wei, Min; Chu, Yong; Li, Huiti; Jiang, Xian-Cheng; Cheng, Nengneng; Zhou, Lu.
Afiliação
  • Li Y; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China; Institute for Agro-food Standards and Testing Technology, Shanghai Academy of Agricultural Sciences, No.1000, Jinqi Rd., Shanghai, 201403, China.
  • Huang T; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China; Eye Ear Nose Throat Hospital, Fudan University, No. 83, Fenyang Rd., Shanghai, 200031, China.
  • Lou B; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Ye D; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Qi X; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Li X; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Hu S; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Ding T; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Chen Y; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Cao Y; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Mo M; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Dong J; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Wei M; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Chu Y; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Li H; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China.
  • Jiang XC; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China; State University of New York Downstate Medical Center, Brooklyn, NY, 11203, USA. Electronic address: xjiang@downstate.edu.
  • Cheng N; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China. Electronic address: chengnn@163.com.
  • Zhou L; School of Pharmacy, Fudan University, No.826, Zhangheng Rd, Shanghai, 201203, China. Electronic address: zhoulu@fudan.edu.cn.
Eur J Med Chem ; 163: 864-882, 2019 Feb 01.
Article em En | MEDLINE | ID: mdl-30580239
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Transferases (Outros Grupos de Fosfato Substituídos) / Aterosclerose / Descoberta de Drogas Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Transferases (Outros Grupos de Fosfato Substituídos) / Aterosclerose / Descoberta de Drogas Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China