Blood-brain and blood-cerebrospinal fluid passage of BRICHOS domains from two molecular chaperones in mice.

Tambaro, Simone; Galan-Acosta, Lorena; Leppert, Axel; Chen, Gefei; Biverstål, Henrik; Presto, Jenny; Nilsson, Per; Johansson, Jan

Tambaro, Simone; Galan-Acosta, Lorena; Leppert, Axel; Chen, Gefei; Biverstål, Henrik; Presto, Jenny; Nilsson, Per; Johansson, Jan.

Afiliação

Tambaro S; From the Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 141 83 Huddinge, Sweden.
Galan-Acosta L; From the Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 141 83 Huddinge, Sweden.
Leppert A; From the Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 141 83 Huddinge, Sweden.
Chen G; From the Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 141 83 Huddinge, Sweden.
Biverstål H; From the Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 141 83 Huddinge, Sweden.
Presto J; From the Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 141 83 Huddinge, Sweden.
Nilsson P; From the Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 141 83 Huddinge, Sweden.
Johansson J; From the Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 141 83 Huddinge, Sweden janne.johansson@ki.se.

J Biol Chem ; 294(8): 2606-2615, 2019 02 22.

Article em En | MEDLINE | ID: mdl-30598503

Assuntos

Peptídeos beta-Amiloides/metabolismo; Barreira Hematoencefálica/metabolismo; Encéfalo/metabolismo; Proteínas de Membrana/sangue; Proteínas de Membrana/líquido cefalorraquidiano; Peptídeos/sangue; Peptídeos/líquido cefalorraquidiano; Proteínas Adaptadoras de Transdução de Sinal; Animais; Permeabilidade da Membrana Celular; Peptídeos e Proteínas de Sinalização Intercelular; Masculino; Proteínas de Membrana/administração & dosagem; Camundongos; Camundongos Endogâmicos C57BL; Peptídeos/administração & dosagem; Domínios Proteicos; Proteína C Associada a Surfactante Pulmonar

Palavras-chave

protein assembly; protein domain; protein misfolding; neuroscience; neurodegenerative disease; protein aggregation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Encéfalo / Barreira Hematoencefálica / Peptídeos beta-Amiloides / Proteínas de Membrana Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suécia

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