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Two new terpenoid ester glycosides from the twigs of Litsea cubeba.
Wang, Ling-Yan; Tian, Ye; Qu, Yu-Hong; Wu, Yu-Zhuo; Li, Yan-Cheng; Li, Rui; Lin, Peng-Cheng; Shang, Xiao-Ya; Lin, Sheng.
Afiliação
  • Wang LY; a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.
  • Tian Y; b National Institutes for Food and Drug Control , Beijing 102629 , China.
  • Qu YH; a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.
  • Wu YZ; a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.
  • Li YC; a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.
  • Li R; a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.
  • Lin PC; c Department of Chemistry and Life Science , Qinghai University for Nationalities , Xining 810007 , China.
  • Shang XY; d Beijing Key Laboratory of Bioactive Substances and Functional Foods , Beijing Union University , Beijing 100023 , China.
  • Lin S; a State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing 100050 , China.
J Asian Nat Prod Res ; 20(12): 1129-1136, 2018 Dec.
Article em En | MEDLINE | ID: mdl-30621451
ABSTRACT
A new sesquiterpenoid ester glycoside (1) and a new monoterpenoid ester glycoside (2) have been isolated from an ethanol extract of the twigs of Litsea cubeba. Their structures were elucidated by extensive 1D- and 2D-NMR experiments, and the absolute configurations were determined by chemical methods, specific rotation, and a combination of experimental and theoretically calculated electronic circular dichroism spectra. Compound 1 exhibited selective cytotoxicity against A549 and HCT-8 cell lines with the IC50 values of 8.9 and 9.6 µM, respectively.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terpenos / Litsea / Glicosídeos Limite: Humans Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terpenos / Litsea / Glicosídeos Limite: Humans Idioma: En Revista: J Asian Nat Prod Res Assunto da revista: BOTANICA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China