Structural transformation-mediated dimerization of caspase recruitment domain revealed by the crystal structure of CARD-only protein in frog virus 3.

Kim, Chang Min; Ha, Hyun Ji; Kwon, Sunghark; Jeong, Jae-Hee; Lee, Sung Hoon; Kim, Yeon-Gil; Lee, Chang Sup; Lee, Jun Hyuck; Park, Hyun Ho

Kim, Chang Min; Ha, Hyun Ji; Kwon, Sunghark; Jeong, Jae-Hee; Lee, Sung Hoon; Kim, Yeon-Gil; Lee, Chang Sup; Lee, Jun Hyuck; Park, Hyun Ho.

Afiliação

Kim CM; College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Ha HJ; College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Kwon S; College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Jeong JH; Pohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang 790-784, Republic of Korea.
Lee SH; Department of Pharmacology, College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea.
Kim YG; Pohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang 790-784, Republic of Korea.
Lee CS; College of Pharmacy and Research Institute of Pharmaceutical Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea.
Lee JH; Unit of Polar Genomics, Korea Polar Research Institute, Incheon 21990, Republic of Korea.
Park HH; College of Pharmacy, Chung-Ang University, Seoul 06974, Republic of Korea. Electronic address: xrayleox@cau.ac.kr.

J Struct Biol ; 205(2): 189-195, 2019 02 01.

Article em En | MEDLINE | ID: mdl-30625366

Assuntos

Proteínas/química; Proteínas/metabolismo; Ranavirus/química; Ranavirus/metabolismo; Apoptose; Domínio de Ativação e Recrutamento de Caspases; Dimerização; Humanos

Palavras-chave

Apoptosis; CARD-only protein; Caspase recruitment domain; Crystal structure; Death domain superfamily; Domain swapping

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas / Ranavirus Limite: Humans Idioma: En Revista: J Struct Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2019 Tipo de documento: Article

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