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HIF-1α metabolically controls collagen synthesis and modification in chondrocytes.
Stegen, Steve; Laperre, Kjell; Eelen, Guy; Rinaldi, Gianmarco; Fraisl, Peter; Torrekens, Sophie; Van Looveren, Riet; Loopmans, Shauni; Bultynck, Geert; Vinckier, Stefan; Meersman, Filip; Maxwell, Patrick H; Rai, Jyoti; Weis, MaryAnn; Eyre, David R; Ghesquière, Bart; Fendt, Sarah-Maria; Carmeliet, Peter; Carmeliet, Geert.
Afiliação
  • Stegen S; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
  • Laperre K; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
  • Eelen G; Laboratory of Angiogenesis and Vascular Biology, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Rinaldi G; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
  • Fraisl P; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Torrekens S; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
  • Van Looveren R; Laboratory of Angiogenesis and Vascular Biology, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Loopmans S; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
  • Bultynck G; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
  • Vinckier S; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
  • Meersman F; Laboratory of Clinical and Experimental Endocrinology, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.
  • Maxwell PH; Laboratory of Molecular and Cellular Signalling, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
  • Rai J; Laboratory of Angiogenesis and Vascular Biology, VIB Center for Cancer Biology, VIB, Leuven, Belgium.
  • Weis M; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium.
  • Eyre DR; Molecular and Nanomaterials, KU Leuven, Leuven, Belgium.
  • Ghesquière B; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
  • Fendt SM; Department of Orthopaedics, University of Washington, Seattle, WA, USA.
  • Carmeliet P; Department of Orthopaedics, University of Washington, Seattle, WA, USA.
  • Carmeliet G; Department of Orthopaedics, University of Washington, Seattle, WA, USA.
Nature ; 565(7740): 511-515, 2019 01.
Article em En | MEDLINE | ID: mdl-30651640
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Ósseas / Colágeno / Condrócitos / Subunidade alfa do Fator 1 Induzível por Hipóxia Limite: Animals Idioma: En Revista: Nature Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Ósseas / Colágeno / Condrócitos / Subunidade alfa do Fator 1 Induzível por Hipóxia Limite: Animals Idioma: En Revista: Nature Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Bélgica