The Unfulfilled Promise of Prokinetics for Functional Dyspepsia/Postprandial Distress Syndrome.
Am J Gastroenterol
; 114(2): 204-206, 2019 02.
Article
em En
| MEDLINE
| ID: mdl-30730856
ABSTRACT
Functional dyspepsia (FD) is subdivided into epigastric pain syndrome and postprandial distress syndrome according to the Rome IV consensus. Based on the assumption that disordered gastric motility is a key pathophysiologic factor in postprandial distress syndrome, prokinetic agents are often proposed as the treatment of choice for this subgroup. Although a meta-analysis suggests that prokinetic agents may be efficacious and safe in FD, there is a lack of widely available agents of proven efficacy. This review analyzes some of the difficulties and challenges in establishing therapeutic efficacy of prokinetic drugs in FD.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dispepsia
Limite:
Humans
Idioma:
En
Revista:
Am J Gastroenterol
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Bélgica