Benzene metabolite hydroquinone promotes DNA homologous recombination repair via the NF-&#954;B pathway.

Yang, Xuejing; Lu, Yedan; He, Fuhong; Hou, Fenxia; Xing, Caihong; Xu, Peiyu; Wang, Qian-Fei

Benzene metabolite hydroquinone promotes DNA homologous recombination repair via the NF-κB pathway.

Yang, Xuejing; Lu, Yedan; He, Fuhong; Hou, Fenxia; Xing, Caihong; Xu, Peiyu; Wang, Qian-Fei.

Afiliação

Yang X; CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Lu Y; Key Laboratory of Chemical Safety and Health, National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
He F; University of Chinese Academy of Sciences, Beijing, China.
Hou F; Key Laboratory of Chemical Safety and Health, National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
Xing C; Department of Nutrition, Food Safety and Toxicology, West China School of Public Health, Sichuan University, Chengdu, Sichuan, China.
Xu P; CAS Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Wang QF; Key Laboratory of Chemical Safety and Health, National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.

Carcinogenesis ; 40(8): 1021-1030, 2019 08 22.

Article em En | MEDLINE | ID: mdl-30770924

Assuntos

Benzeno/toxicidade; Carcinogênese/efeitos dos fármacos; Recombinação Homóloga/efeitos dos fármacos; Hidroquinonas/toxicidade; Benzeno/metabolismo; Carcinogênese/genética; Linhagem Celular; Quebras de DNA de Cadeia Dupla/efeitos dos fármacos; Reparo do DNA/efeitos dos fármacos; Células-Tronco Hematopoéticas; Recombinação Homóloga/genética; Humanos; Hidroquinonas/metabolismo; Mutação/efeitos dos fármacos; NF-kappa B/genética; Fenilenodiaminas/farmacologia; RNA-Seq; Bibliotecas de Moléculas Pequenas/farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzeno / Recombinação Homóloga / Carcinogênese / Hidroquinonas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Carcinogenesis Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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