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Oral administration of a new HRI activator as a new strategy to improve high-fat-diet-induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21.
Zarei, Mohammad; Pujol, Eugènia; Quesada-López, Tania; Villarroya, Francesc; Barroso, Emma; Vázquez, Santiago; Pizarro-Delgado, Javier; Palomer, Xavier; Vázquez-Carrera, Manuel.
Afiliação
  • Zarei M; Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Barcelona, Spain.
  • Pujol E; Spanish Biomedical Research Center in Diabetes and Associated Metabolic Diseases (CIBERDEM), Instituto de Salud Carlos III, Madrid, Spain.
  • Quesada-López T; Pediatric Research Institute, Hospital Sant Joan de Déu, Barcelona, Spain.
  • Villarroya F; Department of Pharmacology, Toxicology and Therapeutic Chemistry, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine of the University of Barcelona (IBUB), University of Barcelona, Barcelona, Spain.
  • Barroso E; Pediatric Research Institute, Hospital Sant Joan de Déu, Barcelona, Spain.
  • Vázquez S; Department of Biochemistry and Molecular Biomedicine, IBUB, University of Barcelona, Barcelona, Spain.
  • Pizarro-Delgado J; Spanish Biomedical Research Center in Physiopathology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.
  • Palomer X; Pediatric Research Institute, Hospital Sant Joan de Déu, Barcelona, Spain.
  • Vázquez-Carrera M; Department of Biochemistry and Molecular Biomedicine, IBUB, University of Barcelona, Barcelona, Spain.
Br J Pharmacol ; 176(13): 2292-2305, 2019 07.
Article em En | MEDLINE | ID: mdl-30927369
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Intolerância à Glucose / EIF-2 Quinase / Diabetes Mellitus Tipo 2 / Fatores de Crescimento de Fibroblastos / Hiperlipidemias / Hipoglicemiantes Limite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Espanha
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Serina-Treonina Quinases / Intolerância à Glucose / EIF-2 Quinase / Diabetes Mellitus Tipo 2 / Fatores de Crescimento de Fibroblastos / Hiperlipidemias / Hipoglicemiantes Limite: Animals / Humans / Male Idioma: En Revista: Br J Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Espanha