Efficacy and safety of secukinumab in active rheumatoid arthritis with an inadequate response to tumor necrosis factor inhibitors: a meta-analysis of phase III randomized controlled trials.

Huang, Yanrong; Fan, Yong; Liu, Yang; Xie, Wenhui; Zhang, Zhuoli

Huang, Yanrong; Fan, Yong; Liu, Yang; Xie, Wenhui; Zhang, Zhuoli.

Afiliação

Huang Y; Department of Rheumatology and Clinical Immunology, Peking University First Hospital, No.8, Xishiku Street, West District, Beijing, 100034, China.
Fan Y; Department of Rheumatology and Clinical Immunology, Peking University First Hospital, No.8, Xishiku Street, West District, Beijing, 100034, China.
Liu Y; Department of Orthopedics, Clinical Sciences, Lund University, 22185, Lund, Sweden.
Xie W; Department of Rheumatology and Clinical Immunology, Peking University First Hospital, No.8, Xishiku Street, West District, Beijing, 100034, China.
Zhang Z; Department of Rheumatology and Clinical Immunology, Peking University First Hospital, No.8, Xishiku Street, West District, Beijing, 100034, China. zhuoli.zhang@126.com.

Clin Rheumatol ; 38(10): 2765-2776, 2019 Oct.

Article em En | MEDLINE | ID: mdl-31087226

Assuntos

Anticorpos Monoclonais Humanizados/uso terapêutico; Artrite Reumatoide/tratamento farmacológico; Inibidores do Fator de Necrose Tumoral/uso terapêutico; Anticorpos Monoclonais Humanizados/efeitos adversos; Antirreumáticos/uso terapêutico; Produtos Biológicos/uso terapêutico; Ensaios Clínicos Fase III como Assunto; Humanos; Segurança do Paciente; Ensaios Clínicos Controlados Aleatórios como Assunto; Risco; Resultado do Tratamento; Inibidores do Fator de Necrose Tumoral/efeitos adversos

Palavras-chave

Efficacy and safety; Rheumatoid arthritis; Secukinumab; Tumor necrosis factor inhibitors

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Anticorpos Monoclonais Humanizados / Inibidores do Fator de Necrose Tumoral Tipo de estudo: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Clin Rheumatol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China

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