Shared and connection-specific intrinsic interactions in the default mode network.
Neuroimage
; 200: 474-481, 2019 10 15.
Article
em En
| MEDLINE
| ID: mdl-31280013
ABSTRACT
Electrophysiological studies revealed that different neuronal oscillations, among which the alpha (8-13â¯Hz) rhythm in particular, but also the beta (13-30â¯Hz) and gamma (30-80â¯Hz) rhythms, are modulated during rest in the default mode network (DMN). Little is known, however, about the role of these rhythms in supporting DMN connectivity. Biophysical studies suggest that lower and higher frequencies mediate long- and short-range connectivity, respectively. Accordingly, we hypothesized that interactions between all DMN areas are supported by the alpha rhythm, and that the connectivity between specific DMN areas is established through other frequencies, mainly in the beta and/or gamma bands. To test this hypothesis, we used high-density electroencefalographic data collected in 19 healthy volunteers at rest. We analyzed frequency-dependent functional interactions between four main DMN nodes in a broad (1-80â¯Hz) frequency range. In line with our hypothesis, we found that the frequency-dependent connectivity profile between pairs of DMN nodes had a peak at 9-11â¯Hz. Also, the connectivity profile showed other peaks at higher frequencies, which depended on the specific connection. Overall, our findings suggest that frequency-dependent connectivity analysis may be a powerful tool to better understand how different neuronal oscillations support connectivity within and between brain networks.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
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Córtex Cerebral
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Eletroencefalografia
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Ondas Encefálicas
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Conectoma
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Rede Nervosa
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Neuroimage
Assunto da revista:
DIAGNOSTICO POR IMAGEM
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Bélgica