Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxo-dodecanoyl)-L-homoserine lactone triggers mitochondrial dysfunction and apoptosis in neutrophils through calcium signaling.

Singh, Pradeep Kumar; Yadav, Vivek Kumar; Kalia, Manmohit; Sharma, Deepmala; Pandey, Deepak; Agarwal, Vishnu

Singh, Pradeep Kumar; Yadav, Vivek Kumar; Kalia, Manmohit; Sharma, Deepmala; Pandey, Deepak; Agarwal, Vishnu.

Afiliação

Singh PK; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, Uttar Pradesh, 211004, India.
Yadav VK; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, Uttar Pradesh, 211004, India.
Kalia M; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, Uttar Pradesh, 211004, India.
Sharma D; Department of Mathematics, National Institute of Technology Raipur, Raipur, Chhattisgarh, 492010, India.
Pandey D; Department of Reproductive Biology, All India Institute of Medical Sciences, New Delhi, 110029, India.
Agarwal V; Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj, Uttar Pradesh, 211004, India. vishnua@mnnit.ac.in.

Med Microbiol Immunol ; 208(6): 855-868, 2019 Dec.

Article em En | MEDLINE | ID: mdl-31377870

Assuntos

4-Butirolactona/análogos & derivados; Apoptose; Sinalização do Cálcio/efeitos dos fármacos; Homosserina/análogos & derivados; Mitocôndrias/efeitos dos fármacos; Neutrófilos/efeitos dos fármacos; Pseudomonas aeruginosa/metabolismo; 4-Butirolactona/metabolismo; Voluntários Saudáveis; Homosserina/metabolismo; Humanos; Neutrófilos/patologia

Palavras-chave

Apoptosis; Calcium signaling; Mitochondria; Neutrophil; ROS; mCU

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / 4-Butirolactona / Apoptose / Sinalização do Cálcio / Homosserina / Mitocôndrias / Neutrófilos Limite: Humans Idioma: En Revista: Med Microbiol Immunol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Índia

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