The small molecule WNT/ß-catenin inhibitor CWP232291 blocks the growth of castration-resistant prostate cancer by activating the endoplasmic reticulum stress pathway.

Pak, Sahyun; Park, Sejun; Kim, Yunlim; Park, Jung-Hyuck; Park, Chan-Hee; Lee, Kyoung-June; Kim, Choung-Soo; Ahn, Hanjong

Pak, Sahyun; Park, Sejun; Kim, Yunlim; Park, Jung-Hyuck; Park, Chan-Hee; Lee, Kyoung-June; Kim, Choung-Soo; Ahn, Hanjong.

Afiliação

Pak S; Department of Urology, Center for Urologic Cancer, National Cancer Center, Goyang, South Korea.
Park S; Department of Urology, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, South Korea.
Kim Y; Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Park JH; Asan Institute for Life Science, Asan Medical Center, Seoul, South Korea.
Park CH; Drug Discovery Center, JW Pharmaceutical Corporation, Seoul, South Korea.
Lee KJ; Drug Discovery Center, JW Pharmaceutical Corporation, Seoul, South Korea.
Kim CS; JW Creagene Corporation, Seongnam, South Korea.
Ahn H; Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

J Exp Clin Cancer Res ; 38(1): 342, 2019 Aug 06.

Article em En | MEDLINE | ID: mdl-31387608

Palavras-chave

Castration-resistant; Endoplasmic reticulum stress; Prostate cancer; WNT signaling pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Coréia do Sul

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