Laterality of breast cancer at Dr George Mukhari Academic Hospital.
S Afr J Surg
; 57(3): 56, 2019 Sep.
Article
em En
| MEDLINE
| ID: mdl-31392868
ABSTRACT
BACKGROUND:
The purpose of this descriptive study was to determine and compare the incidence of left-sided and rightsided breast cancer at Dr George Mukhari Academic Hospital from January 2000 to June 2016. It aimed to determine if there was a significant variation in laterality of breast cancer at our institution.METHOD:
A retrospective study. Medical records of breast cancer (BC) patients who were newly diagnosed from January 2000 to June 2016 were reviewed. Emphasis was on biopsy results (histology and/or cytology) and/or history of chemotherapy, and breast cancer laterality.RESULTS:
Out of 1482 patients, 1427 had unilateral BC and 55 (3.7%) bilateral cancer. A total of 789 (55.3%) patients had left-sided breast cancer (LSBC) and 638 (44.7%) had right BC. Left BC was 10.6% more common than right BC with a left to right laterality ratio (LRR) of 1.24. There was a statistically significant relationship between laterality and stage (p = 0.050), with the right breast having more advanced stage cancers (88.7%) compared to the left breast (85%). There was no statistically significant difference between age, site and histological type of BC and laterality (p = 0.740, p = 0.052, p = 0.394 respectively).CONCLUSION:
Left to right BC excess does exist in patients that were newly diagnosed at Dr George Mukhari Academic Hospital, South Africa, from January 2000 to June 2016.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carcinoma Ductal de Mama
/
Neoplasias da Mama Masculina
/
Neoplasias Unilaterais da Mama
Tipo de estudo:
Incidence_studies
/
Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Africa
Idioma:
En
Revista:
S Afr J Surg
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
África do Sul