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Haploinsufficiency of NR3C1 drives glucocorticoid resistance in adult acute lymphoblastic leukemia cells by down-regulating the mitochondrial apoptosis axis, and is sensitive to Bcl-2 blockage.
Xiao, Haowen; Ding, Yingying; Gao, Yang; Wang, Li-Mengmeng; Wang, Huafang; Ding, Lijuan; Li, Xiaoqing; Yu, Xiaohong; Huang, He.
Afiliação
  • Xiao H; 1Department of Hematology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 Qingchun East Rd., Hangzhou, 310016 Zhejiang People's Republic of China.
  • Ding Y; 2Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang People's Republic of China.
  • Gao Y; Department of Hematology, The People's Hospital of Zhongshan City, Zhongshan, Guangdong Province People's Republic of China.
  • Wang LM; 1Department of Hematology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, No. 3 Qingchun East Rd., Hangzhou, 310016 Zhejiang People's Republic of China.
  • Wang H; 2Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang People's Republic of China.
  • Ding L; 4Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Rd., Hangzhou, 310003 Zhejiang People's Republic of China.
  • Li X; 2Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang People's Republic of China.
  • Yu X; 4Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Rd., Hangzhou, 310003 Zhejiang People's Republic of China.
  • Huang H; 2Institute of Hematology, Zhejiang University, Hangzhou, Zhejiang People's Republic of China.
Cancer Cell Int ; 19: 218, 2019.
Article em En | MEDLINE | ID: mdl-31462891
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Cancer Cell Int Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Cancer Cell Int Ano de publicação: 2019 Tipo de documento: Article