A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission.

Liskovykh, Mikhail; Goncharov, Nikolay V; Petrov, Nikolai; Aksenova, Vasilisa; Pegoraro, Gianluca; Ozbun, Laurent L; Reinhold, William C; Varma, Sudhir; Dasso, Mary; Kumeiko, Vadim; Masumoto, Hiroshi; Earnshaw, William C; Larionov, Vladimir; Kouprina, Natalay

Liskovykh, Mikhail; Goncharov, Nikolay V; Petrov, Nikolai; Aksenova, Vasilisa; Pegoraro, Gianluca; Ozbun, Laurent L; Reinhold, William C; Varma, Sudhir; Dasso, Mary; Kumeiko, Vadim; Masumoto, Hiroshi; Earnshaw, William C; Larionov, Vladimir; Kouprina, Natalay.

Afiliação

Liskovykh M; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Goncharov NV; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Petrov N; School of Biomedicine, Far Eastern Federal University, A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch of Russian Academy of Sciences, Vladivostok, 690000, Russia.
Aksenova V; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Pegoraro G; Division of Molecular and Cellular Biology, National Institute for Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
Ozbun LL; High-Throughput Imaging Facility, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Reinhold WC; High-Throughput Imaging Facility, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Varma S; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Dasso M; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Kumeiko V; Division of Molecular and Cellular Biology, National Institute for Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
Masumoto H; School of Biomedicine, Far Eastern Federal University, A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch of Russian Academy of Sciences, Vladivostok, 690000, Russia.
Earnshaw WC; Laboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, Kisarazu, Chiba 292-0818d, Japan.
Larionov V; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom.
Kouprina N; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

Genome Res ; 29(10): 1719-1732, 2019 10.

Article em En | MEDLINE | ID: mdl-31515286

Assuntos

Instabilidade Cromossômica/genética; Cromossomos Humanos/genética; Proteínas Quinases/genética; RNA Interferente Pequeno/genética; Aneuploidia; Proteína Quinase Tipo 1 Dependente de Cálcio-Calmodulina/genética; Linhagem Celular Tumoral; Cromossomos Artificiais Humanos/genética; Fatores de Troca do Nucleotídeo Guanina/genética; Humanos; Quinases Associadas a Receptores de Interleucina-1/genética; Mitose/genética; Proteínas Quinases/isolamento & purificação; Proteínas Serina-Treonina Quinases/genética; RNA de Cadeia Dupla/genética; Transgenes; Translocação Genética/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Cromossomos Humanos / RNA Interferente Pequeno / Instabilidade Cromossômica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Genome Res Assunto da revista: BIOLOGIA MOLECULAR / GENETICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

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