Role of Supramolecule ErpY-Like Lipoprotein of <i>Leptospira</i> in Thrombin-Catalyzed Fibrin Clot Inhibition and Binding to Complement Factors H and I, and Its Diagnostic Potential.

Ghosh, Karukriti Kaushik; Prakash, Aman; Dhara, Anusua; Hussain, Md Saddam; Shrivastav, Prateek; Kumar, Pankaj; Balamurugan, Vinayagamurthy; Kumar, Manish

Role of Supramolecule ErpY-Like Lipoprotein of Leptospira in Thrombin-Catalyzed Fibrin Clot Inhibition and Binding to Complement Factors H and I, and Its Diagnostic Potential.

Ghosh, Karukriti Kaushik; Prakash, Aman; Dhara, Anusua; Hussain, Md Saddam; Shrivastav, Prateek; Kumar, Pankaj; Balamurugan, Vinayagamurthy; Kumar, Manish.

Afiliação

Ghosh KK; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, India.
Prakash A; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, India.
Dhara A; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, India.
Hussain MS; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, India.
Shrivastav P; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, India.
Kumar P; ICAR Research Complex for Eastern Region-ICAR Parisar, Patna, India.
Balamurugan V; Indian Council of Agricultural Research-National Institute of Veterinary Epidemiology and Disease Informatics (ICAR-NIVEDI), Bengaluru, India.
Kumar M; Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, India mkumar1@iitg.ac.in.

Infect Immun ; 87(12)2019 12.

Article em En | MEDLINE | ID: mdl-31548314

Assuntos

Proteínas da Membrana Bacteriana Externa/metabolismo; Coagulação Sanguínea/fisiologia; Fator H do Complemento/metabolismo; Fator I do Complemento/metabolismo; Leptospira/imunologia; Leptospirose/diagnóstico; Animais; Dicroísmo Circular; Via Alternativa do Complemento/imunologia; Feminino; Tempo de Lise do Coágulo de Fibrina; Lipoproteínas/metabolismo; Camundongos; Camundongos Endogâmicos BALB C; Ligação Proteica; Estrutura Secundária de Proteína; Trombina/metabolismo

Palavras-chave

ELISA; LIC11966; Leptospira; antibodies; extracellular matrix component; factor H; fibrinogen; lipoprotein; recombinant protein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas da Membrana Bacteriana Externa / Coagulação Sanguínea / Fator I do Complemento / Fator H do Complemento / Leptospira / Leptospirose Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Revista: Infect Immun Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Índia

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