Mat_peptide: comprehensive annotation of mature peptides from polyproteins in five virus families.
Bioinformatics
; 36(5): 1627-1628, 2020 03 01.
Article
em En
| MEDLINE
| ID: mdl-31609421
ABSTRACT
MOTIVATION Sequence repositories have few well-annotated virus mature peptide sequences. Therefore post-translational proteolytic processing of polyproteins into mature peptides (MPs) has been performed in silico, with a new computational method, for over 200 species in 5 pathogenic virus families (Caliciviridae, Coronaviridae, Flaviviridae, Picornaviridae and Togaviridae). RESULTS:
Using pairwise alignment with reference sequences, MPs have been annotated and their sequences made available for search, analysis and download. At publication the method had produced 156 216 sequences, a large portion of the protein sequences now available in https//www.viprbrc.org. It represents a new and comprehensive mature peptide collection. AVAILABILITY AND IMPLEMENTATION The data are available at the Virus Pathogen Resource https//www.viprbrc.org, and the software at https//github.com/VirusBRC/vipr_mat_peptide.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vírus
/
Poliproteínas
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2020
Tipo de documento:
Article