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The metabolic and vascular protective effects of olive (Olea europaea L.) leaf extract in diet-induced obesity in mice are related to the amelioration of gut microbiota dysbiosis and to its immunomodulatory properties.
Vezza, Teresa; Rodríguez-Nogales, Alba; Algieri, Francesca; Garrido-Mesa, José; Romero, Miguel; Sánchez, Manuel; Toral, Marta; Martín-García, Beatriz; Gómez-Caravaca, Ana M; Arráez-Román, David; Segura-Carretero, Antonio; Micol, Vicente; García, Federico; Utrilla, María Pilar; Duarte, Juan; Rodríguez-Cabezas, María Elena; Gálvez, Julio.
Afiliação
  • Vezza T; CIBER-EHD, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, 18071, Granada, Spain; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain.
  • Rodríguez-Nogales A; Allergy Research Group, Instituto de Investigación Biomédica de Málaga-IBIMA, Málaga, Spain. Electronic address: albarnogales@gmail.com.
  • Algieri F; CIBER-EHD, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, 18071, Granada, Spain.
  • Garrido-Mesa J; CIBER-EHD, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, 18071, Granada, Spain.
  • Romero M; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain; CIBER-Enfermedades Cardiovasculares, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, 18071, Granada, Spain.
  • Sánchez M; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain; CIBER-Enfermedades Cardiovasculares, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, 18071, Granada, Spain.
  • Toral M; Gene Regulation in Cardiovascular Remodeling and Inflammation Group, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
  • Martín-García B; Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avenida Fuentenueva s/n, 18071, Granada, Spain; Research and Development Centre for Functional Food (CIDAF), PTS Granada, 18016, Granada, Spain.
  • Gómez-Caravaca AM; Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avenida Fuentenueva s/n, 18071, Granada, Spain; Research and Development Centre for Functional Food (CIDAF), PTS Granada, 18016, Granada, Spain.
  • Arráez-Román D; Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avenida Fuentenueva s/n, 18071, Granada, Spain; Research and Development Centre for Functional Food (CIDAF), PTS Granada, 18016, Granada, Spain.
  • Segura-Carretero A; Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avenida Fuentenueva s/n, 18071, Granada, Spain; Research and Development Centre for Functional Food (CIDAF), PTS Granada, 18016, Granada, Spain.
  • Micol V; CIBERobn, Instituto de Salud Carlos III (CB12/03/30038), Institute of Molecular and Cell Biology (IMCB), Miguel Hernández University (UMH), 03202, Elche, Alicante, Spain.
  • García F; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain; Clinical Microbiology Service, Hospital Universitario San Cecilio, Red de Investigación en SIDA, Granada, Spain.
  • Utrilla MP; CIBER-EHD, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, 18071, Granada, Spain; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain.
  • Duarte J; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain; CIBER-Enfermedades Cardiovasculares, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, 18071, Granada, Spain.
  • Rodríguez-Cabezas ME; CIBER-EHD, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, 18071, Granada, Spain; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain.
  • Gálvez J; CIBER-EHD, Department of Pharmacology, Center for Biomedical Research (CIBM), University of Granada, 18071, Granada, Spain; Instituto de Investigación Biosanitaria de Granada (ibs.GRANADA), Granada, Spain.
Pharmacol Res ; 150: 104487, 2019 12.
Article em En | MEDLINE | ID: mdl-31610229
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Fármacos Antiobesidade / Olea / Disbiose / Fatores Imunológicos / Obesidade Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Espanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Fármacos Antiobesidade / Olea / Disbiose / Fatores Imunológicos / Obesidade Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Espanha