Kidney-based in vitro models for drug-induced toxicity testing.

Faria, João; Ahmed, Sabbir; Gerritsen, Karin G F; Mihaila, Silvia M; Masereeuw, Rosalinde

Faria, João; Ahmed, Sabbir; Gerritsen, Karin G F; Mihaila, Silvia M; Masereeuw, Rosalinde.

Afiliação

Faria J; Division of Pharmacology, Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.
Ahmed S; Division of Pharmacology, Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.
Gerritsen KGF; Department of Nephrology and Hypertension, University Medical Center, Utrecht, The Netherlands.
Mihaila SM; Division of Pharmacology, Department of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.
Masereeuw R; Department of Nephrology and Hypertension, University Medical Center, Utrecht, The Netherlands.

Arch Toxicol ; 93(12): 3397-3418, 2019 12.

Article em En | MEDLINE | ID: mdl-31664498

Assuntos

Nefropatias/induzido quimicamente; Rim/efeitos dos fármacos; Testes de Toxicidade/métodos; Animais; Biomarcadores Farmacológicos/análise; Humanos; Técnicas In Vitro; Rim/fisiopatologia; Testes de Toxicidade/instrumentação

Palavras-chave

Biomarkers; Drug-induced kidney injury; In vitro models; Nephrotoxicity

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Testes de Toxicidade / Rim / Nefropatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Arch Toxicol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda

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