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Oligodendroglioma with Neuronal Differentiation in Two Boxer Dogs.
Cornax, I; Pluhar, G E; Clark, H B; O'Sullivan, M G.
Afiliação
  • Cornax I; Comparative Pathology Shared Resource, Masonic Cancer Center, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
  • Pluhar GE; Department of Veterinary Clinical Sciences, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
  • Clark HB; Department of Laboratory Medicine and Pathology, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA.
  • O'Sullivan MG; Comparative Pathology Shared Resource, Masonic Cancer Center, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA; Department of Veterinary Population Medicine, College of Veterinary Medicine, Medical School, University of Minnesota - Twin Cities, Minneapolis, MN, USA. Electr
J Comp Pathol ; 172: 11-16, 2019 Oct.
Article em En | MEDLINE | ID: mdl-31690408
ABSTRACT
Two cases of high-grade glioma comprising sheets of oligodendroglial cells multifocally disrupted by regions of remarkable neuronal differentiation are described. These tumours morphologically resemble 'oligodendroglioma with ganglioglioma-like maturation', a rare tumour of man, but appear to be phenotypically more aggressive. Neuronal markers (synaptophysin, neuron-specific enolase and ßIII-tubulin) effectively highlight neuronal elements within these tumours and could potentially help to further investigate the prevalence and biological significance of neuronal differentiation in canine oligodendroglioma.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligodendroglioma / Fosfopiruvato Hidratase / Tubulina (Proteína) / Neoplasias Encefálicas / Sinaptofisina / Doenças do Cão Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: J Comp Pathol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligodendroglioma / Fosfopiruvato Hidratase / Tubulina (Proteína) / Neoplasias Encefálicas / Sinaptofisina / Doenças do Cão Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: J Comp Pathol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos