Oligodendroglioma with Neuronal Differentiation in Two Boxer Dogs.
J Comp Pathol
; 172: 11-16, 2019 Oct.
Article
em En
| MEDLINE
| ID: mdl-31690408
ABSTRACT
Two cases of high-grade glioma comprising sheets of oligodendroglial cells multifocally disrupted by regions of remarkable neuronal differentiation are described. These tumours morphologically resemble 'oligodendroglioma with ganglioglioma-like maturation', a rare tumour of man, but appear to be phenotypically more aggressive. Neuronal markers (synaptophysin, neuron-specific enolase and ßIII-tubulin) effectively highlight neuronal elements within these tumours and could potentially help to further investigate the prevalence and biological significance of neuronal differentiation in canine oligodendroglioma.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oligodendroglioma
/
Fosfopiruvato Hidratase
/
Tubulina (Proteína)
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Neoplasias Encefálicas
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Sinaptofisina
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Doenças do Cão
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
Idioma:
En
Revista:
J Comp Pathol
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Estados Unidos